Bioavailability Of Buprenorphine From Crushed And Entire Buprenorphine (subutex) Tablets – PubMed
Strategies: A complete of sixteen opioid-dependent patients stabilized on 24 mg of buprenorphine have been enrolled in a double-blind, double-dummy, randomized cross-over examine comparing crushed and whole buprenorphine tablets on a spread of pharmacokinetic and pharmacodynamic variables. Buprenorphine tablets (either crushed or complete) and placebo tablets (both crushed or complete) had been administered to subjects …